Southeast Asia, including Indonesia, is very vulnerable to new infectious diseases due to viruses. Indonesia itself is in an area that is classified as very vulnerable to the spread (outbreak) of this new virus. Disease-causing viruses are viruses that can infect and multiply in human cells. The continued emergence of various new viruses and
Southeast Asia, including Indonesia, is very vulnerable to new infectious diseases due to viruses. Indonesia itself is in an area that is classified as very vulnerable to the spread (outbreak) of this new virus.
Disease-causing viruses are viruses that can infect and multiply in human cells. The continued emergence of various new viruses and re-emerging old viruses has become a major problem in human health.
“Indonesia is listed as the country with the highest death toll due to infection with the influenza A / H5N1 virus (bird flu virus),” said Prof. Dr. Ir. I Made Artika, in his press statement.
New diseases arising or recurring due to viral infections have become a global problem and increasingly threaten the health of the world community. History has proven that the emergence of new viruses is increasingly frequent. In 1918, the Spanish flu virus emerged, which killed millions of people. After that, a number of new viruses appeared, but the time they appeared was relatively rare. In recent years, the appearance of new viruses has become more frequent.
Not over the Ebola virus crisis in West Africa, the Zika virus appeared in South America and then followed the emergence of the Corona virus, SARS-CoV-2, in Wuhan, China, causing a pandemic. This proves how vulnerable the world community is to viral infections.
“When and where a new virus will appear is very difficult to predict. A new virus that has the potential to cause major disasters in the health sector, can appear anywhere, including in areas with limited detection capabilities. The absence of reports on the circulation of a particular virus in an area does not always mean that the area is free from the virus, but it could also be due to limited detection capabilities, “he said.
Therefore, Prof. Made hopes that each region or country needs to develop the capacity to detect and characterize viruses. In addition, considering that virus handling has the potential to cause infection in laboratory personnel, the application of safety principles (biosafety) is very important to reduce the risk of exposure to and viral infection. Furthermore, the development of vaccines and antiviral drugs is needed to prevent and treat viral diseases and molecular techniques can also be applied to the development of vaccines and antiviral drugs.
“Given that the emergence of new viruses is very difficult to predict, each region needs to build virus handling preparedness, including the capacity for detection, characterization, and vaccine and antiviral drug development. Indonesia is located in an area that is classified as very vulnerable to the spread (outbreak) of new viruses, so Indonesia needs to seek a strategy to address this problem, including through scientific and technical development in the fields of biochemistry and molecular biology, “he explained.
He said, advances in molecular biology techniques have revolutionized methods of detection and characterization of viruses. In particular, the polymerase chain reaction (PCR) technique and DNA sequencing technology are very sensitive and specific methods for determining the type of virus circulating. Both of these techniques have been used extensively in the detection and characterization of disease-causing viruses in humans.
“In principle, these two techniques mimic biological phenomena that occur in nature, especially the DNA replication process which involves the role of the DNA polymerase and primer enzymes. Molecular biology techniques are techniques commonly applied in the field of biochemistry and molecular biology that involve the analysis and manipulation of RNA, DNA, proteins, and lipids.
Currently, almost all fields of life involve studies at the molecular level and apply molecular biology techniques. Therefore, biochemistry and molecular biology play an important role in underlying the development and advancement of knowledge in the fields of agriculture, health, industry and the environment, “he concluded. newstrubus.id